Pharmacognostic Profile and Antibacterial Activity of Aerial Parts of Chenopodiastrum Murale (Research Article)

Author(s): Shivam Chaurasia*, Vijay Nigam, Jagrati Chaurasia, Shivam khare, Anshul Rajpoot and Anmol Agarwal

Abstract: Nettleleaf goosefoot was observed on Chenopodium murale at Barapani, Meghalaya, India. C. murale is used as a leafy vegetable in the north-eastern hills region of India. This species is mainly regarded as a summer weed in the Mediterranean region. The antibacterial activity of crude petroleum ether, benzene, chloroform, acetone, ethanol and aqueous extracts of Chenopodiastrum murale aerial parts were tested against Staphylococcus capitis, Staphylococcus mutans, Pseudomonas mirabilis and Bacillus fragillis. The in vitro antibacterial activity was performed by agar disc diffusion method. The zone of inhibition was compared with the standard drug i.e. Penicillin. Petroleum ether, chloroform, acetone and ethanol extracts were effective against the entire four test microorganism used respectively when compared to standard drug penicillin. The minimum inhibitory concentration [MIC] for S.capitis was 10,750,10,10,10 and 1000 mg/ml; MIC for S.mutans was 10,125,10,10,10 and 10 mg/ml; MIC for P.mirabilis was 20, 10,10,10,20 and 10 mg/ml and MIC for B.fragillis was 10,10,10,20,10 and 20 mg/ml for petroleum ether, benzene, chloroform, acetone, ethanol and aqueous extracts respectively suggesting the antibacterial activity of Chenopodiastrum murale. Acetone extract was more effective followed by ethanol extract as antibacterial agents when compared to other extracts of aerial parts of Chenopodiastrum murale. Leaves and young shoots - raw or cooked as spinach. The raw leaves should only be eaten in small quantities, see the notes above on toxicity. Seed - cooked. It can be ground into a powder and mixed with wheat or other cereals and used in making bread etc.Work is under progress to reveal the chemical nature of the active constituents responsible for the antibacterial activity.

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