Drug Utilization Research in Adult Patients with Type 2 Diabetes (Research Article)

Author(s): Naveen Poojar C M*, Sudhindra D and Ujwala N J

Abstract: Background: Diabetes mellitus is an important public health problem in developing countries like India. Various classes of anti-diabetic drugs including Insulin and oral hypoglycemic agents are currently being used in the treatment of diabetes, which acts by various mechanisms to reduce the blood glucose levels in order to maintain optimal glycemic control. The drug utilization research is important in clinical practice. Irrational drug use can lead to adverse outcomes of the disease. Objectives: The objective of this study was to evaluate the pattern of drugs used in Type II diabetes mellitus and their rationality and to identify any immediate adverse drug reactions, related to drugs administered. Methods: Prospective, observational study was conducted for 6 months including 200 patients with Type 2 Diabetes Miletus in IPD and OPD of Primary care hospital in the South Bengaluru. Results: Biguanide (Metformin) is the most commonly used drug with 84% of patients followed by Sulfonylureas in 48%, DPP-4 inhibitor in 42% and Human Insulin in 14% of the patients. Fixed drug combination prescribed in 172 (86%) among total prescriptions. Two drug combinations 124 (62%) and three drug combination 48 (24%). Conclusion: In this study, the prescribing trend was found to be dual drug therapy. Among oral antidiabetic agents, Metformin was most commonly used drug.

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