Stability Indicating RP-HPLC Method Development and Validation for Estimation of Safinamide in Bulk Drug and Dosage Form (Research Article)

Author(s): Gayatri R. Amrutkar*, Smita S Aher and R S Bachhav

Abstract: This research article emphasizes on this research, a novel, sensitive, convenient, clear, accurate, and robust reverse-phase high-performance liquid chromatography (RP-HPLC) method was developed and validated for the determination of safinamide in drug and tablet formulation. Separation was performed by HPLC with UV detector and Open lab EZchrome workstation program, as well as Kromasil C18 (250 mm X 4.6 mm i.d.) 5 μm. Methanol: 0.025% TFAA (45:55) was pumped at a flow rate of 1.0 mL/min and detected at 226 nm.

PAGES: 92-106  |  76 VIEWS  50 DOWNLOADS