Comparison of Quantitative POCT Plasma D Dimer Values With Semiautomated Method (Research Article)

Author(s): R.D.Malathi, Jyotsna Volturi* and Dawood Suleman

Abstract: Background and Aim: D Dimer is a soluble fibrin degradation product, the estimation of which is used to identify intravascular thrombosis. Different types of D Dimer assays are available commercially which help to diagnose VTE/PE/DIC. The aim of this study was to compare plasma D Dimer values on POCT and Semi-auto analyser over random samples received in the lab and correlate the performance of both. Method: A prospective observational study conducted in a tertiary care hospital in Telangana. Results: Main outcome measures were the statistical correlation of the two methods. The results showed that there was strong correlation of POCT D-Dimer values with Semi-automated method. The correlation between the two was significant with r value of 0.846. When subjected to regression analysis, it was not significant indicating that both values were almost comparable and that POCT was not superior to Semi automated method. Conclusion: The POCT device was comparable with existing Semiautoanalyzer and can be used for reliable estimation of D Dimer.

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