Volume 11, Issue 1, January 2021

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Antimicrobial Potential of Ocimum sanctum and Adhatoda vasica: The Medicinal Herbs (Review Article)

Author(s): Mishra. T* and Rai. A
Abstract: In the present review an attempt has been made to congregate the ethnomedicinal, botanical, phytochemical, and toxicological information on Ocimum sanctum and Adhatoda vasica, the medicinal herbs used in the indigenous system of medicine. The antimicrobial potential of O. sanctum and A. vasica against some selected human pathogens causing infection have been evaluated by taking different extracts. Agar well diffusion method has been employed for evaluation of antimicrobial potentials. The minimum inhibitory (MIC) concentration of test agents was determined by serial dilution method. Aqueous extract of Tulsi has shown inhibitory effect on E. coli, Bacillus subtilis, Salmonella newport, Proteus vulgaris, Klebsiella aerogens while ethanolic extracts of Adhatoda vasica was found to be more effective. Alcoholic and ethanolic extracts of O. sanctum and A. vasica shown inhibitory effect against Vibrio cholerae. Antifungal effect shown by aqueous and methanolic extract of O. Sanctum and A.vasica against Candida albicans, Candida tropicalis and Cryptococcus marinus. Different chemical constituents of Tulsi such as apigenin, linalool and urosolic acid exhibited antiviral effect against Herpes simplex virus (HSV-1 and HSV-2), Adeno virus (ADV-8), Coxsackie virus B1 (CVB), enterovirus 71 (EV 71). Antiviral potential of A. vasica also shown by aqueous and methanolic extracts more effectively in Influenza virus. Therefore, it can be concluded that O. sanctum and A. vasica possess antimicrobial activity which can be further explored for the development of formulation and their structural elucidation.
PAGES: 17-28  |  24 VIEWS  148 DOWNLOADS

How To Cite this Article:

Mishra. T* and Rai. A. Antimicrobial Potential of Ocimum sanctum and Adhatoda vasica: The Medicinal Herbs (Review Article). 2021; 11(1): 17-28.