Volume 10, Issue 4, October 2020

Case Report on Antibiotic Allergy Intolerance (Case Report)

Author(s): Parvathy Rajan P, Priscilla Mary, Sheik Haja Sherief and Sivakumar T
Abstract: The discovery of antibiotics from 20th century onwards have helped humans to fight against deadly diseases, but the more we use them, it is greater the pressure on bacteria to evolve and flourish. Pathogens emerge different mechanisms and mutations to beat a particular drug where after such population develops among bacterium, evolving resistance. This makes the patients longer to recover or less likely to survive. Other important cofactor on antibiotic use is the allergic reaction that patients develops, diagnosing true drug allergy can be very challenging and it is very crucial that patients are managed appropriately otherwise antibiotics needs to get withheld unnecessarily, which would affect clinical outcomes, increasing healthcare costs and potentially contributing to forth new drug-resistant bacteria. This is a case report of 19-year-old male patient admitted in the hospital for the complaints of reinfection on the site of fracture with ex fix in- situ application. He was newly diagnosed for allergic reaction to ofloxacin and cotrimoxazole. He was initially on INJ. CEFUROXIME 1.5 gm, later based on the culture results, he being resistant to cefuroxime it was mandatory to switch to INJ.OFLOXACIN 200mg. On the test dose patient developed allergic reaction to INJ.OFLOXACIN 200mg consequently INJ.COTRIMOXAZOLE (160/800) mg 1-0-1 was advised as an alternative, unfortunately patient developed allergic episode on cotrimoxazole furthermore. It is challenging for a multidisciplinary team about the possible consequences of labelling a patient with an antibiotic allergy; with their subsequent impacts on patient therapeutic outcomes and how a clinical pharmacist can undertake appropriate investigations and de label patients.
PAGES: 63-66  |  27 VIEWS  36 DOWNLOADS

How To Cite this Article:

Parvathy Rajan P, Priscilla Mary, Sheik Haja Sherief and Sivakumar T. Case Report on Antibiotic Allergy Intolerance (Case Report). 2020; 10(4): 63-66.