Pharmacognostical and Pharmaceutical Analysis of Sanjivani vati-An Ayurvedic Polyherbal Formulation (Research Article)

Author(s): Chaitali Kakadiya, Mandip Goyal, C. R. Harisha and V. J. Shukla

Abstract: Sanjivani Vati is a polyherbal formulation containing various Ayurvedic medicinal drugs and is mentioned in Sharangadhara Samhita, specially indicated for the treatment of Ama, Ajirna, Gulma, Visuchika, Sarpavisha and in the condition of Sannipata. For assurance of quality of herbal compounds pharmacognostical and pharmaceutical analysis should be done. Methods: Sanjivani Vati was subjected to microscopic evaluation for pharmacognostical study, physic-chemical analysis like hardness, weight variation, loss on drying, ash value, acid insoluble extract, pH value, water soluble extract, alcohol soluble extract, and high Performance thin layer chromatography(HPTLC). Results: Pharmacognostical study showed the presence of certain identifying characters of all of the ingredients of Sanjivani Vati that is Vidanga, Shunthi, Pippali, Haritaki, Bibhitaki, Amalaki, Vacha, Guduchi, Bhallataka, Vatsanabha and Gomutra (Bhavana Dravya). In pharmaceutical study, preliminary physico-chemical analysis showed that hardness of Vati was 6.9 Kg/cm2 ash value 14.03%w/w, acid insoluble ash value 0.3%w/w, loss on drying 16.44%w/w, water soluble extract 32.565w/w, alcohol soluble extract 13.94%w/w. HPTLC analysis showed eleven spots in 254nm and seven spots in 366nm. Conclusion: Present work was carried out to standardize the polyherbal formulation Sanjivani Vati in terms of its identity, quality and purity. Pharmacognostical and physico-chemical observations revealed the specific characters of all active constituents in the preparation and it was found to be suitable as per the parameters of API.

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