Phytochemical and Anthelmintics Activity of Phyllanthus reticulatus (Poir)

Author(s): Mythili A*

Abstract: Aim and objective: Phyllanthus reticulatus poir is used to treat many diseases and used as antidiabetic, antiplasmodial activity, Hypocholesterolemic activity, Antimicrobials, Cytotoxic activity, Hepatoprotective activity., etc. The present study was aimed to separate phytochemicals present in it and analysis of its anthelmintic activity. Materials and methods: Phyllanthus reticulate poir leaves are shade dried and coarsely Powdered plant leaves were used for the extraction purposes. It was extracted with various solvents such as petroleum ether, chloroform, ethyl acetate and ethanol. Extracted materials were subjected to phytochemical analysis and to found anthelmintic activity of it against Peritima posthuma. Results and discussion: Phytochemical screening of the extracts revealed the presence of Carbohydrates, Proteins, Phytosterols, Alkaloids, Saponins, Flavonoids, Terpenoids, Tannins and Steroids. It was found that Ethanolic and Aqueous extract exhibited anthelmintic activity in dose dependent manner Giving the shortest time of paralysis and death with 60mg/ml concentration. Conclusion: The ethyl acetate and alcoholic extract of Phyllanthus reticulatus poir Wight & Arm not only demonstrated paralysis, but also caused death of worms especially at higher concentration of 60 mg per ml is shorter time as compared to that reference drug Albendazole. The data suggested that the Aqueous extract has more significant anthelmintic activity then ethanolic extract.

PAGES: 38-43  |  52 VIEWS  52 DOWNLOADS