Studies on the Synthesis, Characterization and Antibacterial Properties of Green-Synthesized Silver Nanoparticles from Whole Plant Aqueous extracts of Gynura lycopersicifolia DC

Author(s): Mulla Khaja peer and *Nimmanapalli Yasodamma

Abstract: Today green synthesis of silver nanoparticles (SNPs) from plants is an utmost emerging field in nanotechnology. In the present study, reported the synthesis of SNPs from aqueous whole plant extract of Gynura lycopersicifolia. These green-synthesized nanoparticles are characterized by colour change pattern, and the broad peak obtained at 445 nm, with UV–Vis surface Plasmon resonance studies confirm the synthesis of SNPs. FT-IR spectroscopic studies shows the presence of phenols and proteins mainly responsible for capping and stability of synthesized SNPs. Crystallographic studies from XRD indicates, the SNPs are crystalline in nature owing to 50 nm size. EDAX analysis shows 62.53% weight percentage of Ag metal in the sample indicates the purity of sample. And TEM microscopic study reveals the nanoparticles are spherical in shape with size ranging from 10 to 50 nm. Antibacterial studies of the synthesized SNPs on clinically isolated bacterial strains showed effective susceptibility towards Klebsiella pneumonia with 26.5 mm diameter zone of inhibition, at 40μl concentration. It indicates that whole plant extract of Gynura lycopersicifolia is suitable for synthesizing stable silver nanoparticles which act as excellent anthelmintic, antiseptic, against depressions and also as best antibacterial agent, may be due to the presence of phenolic compounds, flavonoids, glycosides and alkaloids.

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