In Vivo Anti Cancer Activity of Novel 2-Phenyl-1-Benzofuranone Derivatives on Sarcoma Induced Mice by Histopathological Examination

Author(s): Raghava Doonaboyina*, Abhilasha Mittal and Gummadi Sridhar Babu

Abstract: The newly synthesized compounds are being tested for in vitro anti-cancer activity. Method used for In Vitro testing is Sulforhodamine B assay also known SRB assay. The best resulted compounds were tested for In Vivo studies in sarcoma induced mice. Sarcoma induced to mice by using direct induction ascites to the mice. Doxorubicin was the standard drug for the comparison results of the synthesized drugs. The obtained samples were examined hematoxylin with eosin staining and under rotary microscope. Samples PG1A & HLVC exhibited optimized results.

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