Evaluation of In Vitro Antidiabetic Effect of Chitosan from Lobster (Panulirus ornatus) Shell

Author(s): Balu Arasukumar, Gopal Prabakaran and B. Gunalan

Abstract: The present study was aimed to extract the chitosan from the chitin complex by chemical method and screening their antidiabetic potential by in vitro assays from the lobster Panulirus ornatus shell. The chitin yield was calculated for 21% and the chitosan was obtained from the chitin by deacetylation process and the yield was found to be 35%. The α-amylase inhibition potential of chitosan has showed concentration depended and the maximum activity 64% was recorded at 1000 μg/ml and the minimum activity 16% was recorded at 200μg/ml. The β-glucosidase inhibition potential of chitosan has showed dose depended and the maximum activity was 43% showed at 1000μg/ml and the minimum effect 11% was noticed 200μg/ml. Chitosan and alternate source for the development of antidiabetic drug development.

PAGES: 12-15  |  28 VIEWS  39 DOWNLOADS