Cytotoxic Activity of Ayurvedic Polyherbal Product Muneks On Selected Cell Lines

Author(s): Badekila Sathyanarayana

Abstract: In-vitro cytotoxicity of Muneks tablet was tested by MTT for A549 (Human Lung Carcinoma), HeLa (Human Cervix Adenocarcinoma), SKOV3 (Human ovarian cancer), CaCo2 (Human Colon carcinoma), MDA-MB 231 (Human breast cancer), JURKAT 3 (Human leukemia), HL-60 (Human leukemia) and LN Cap (Human prostate Adenocarcinoma) cell lines. Muneks tablet was taken at concentrations ranging from 1000 μg/ml to 7.8μg/ml to determine the percentage growth inhibition on the cell lines A549, HeLa, SKOV3, CaCo2, MDA MB 231, JURKAT, HL-60 and LN Cap. The Muneks exhibited a CTC50 value of 117.71±2.37, 202.39±4.25, 94.28±2.06, 155.86±1.03, 167.47±4.48, 277.03±3.15, 312.81±4.78 and 231.51±3.61 respectively.

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