Determination of Physicochemical and Phytochemical Potential of Sesamum Indicum L. Seeds (Kunjad Sufaid)

Author(s): Zafar Javed Khan*, Naeem Ahmad Khan, Imrana Naseem and Shahab A A Nami

Abstract: Background: Proper identification and standardization is mandatory to ensure the therapeutic efficacy of herbal drugs used for health ailments. Physicochemical and Phytochemical standardization is considered a prerequisite for the assessment, of biological activity or determination of biological standards of the plant material. It provides the analytical characteristics which may prove to be useful in fixing the physicochemical standard for the Unani drugs. Unani Medicine possess a large number of drugs used in various diseases as mentioned by eminent Unani Physicians based on their own long-term experience. But, a doubt always remains regarding the standardization of Unani drugs. Objective: Therefore, the present study was aim to standardize and to assure the quality control check of an important Unani drug Kunjad safaid used for various infectious diseases. Material and Methods: The test drugs, Kunjad (Sesamum indicum L.) were procured from local market of Aligarh. Which includes parameters recommended by National Unani Pharmacopeia Committee, Qualitative analysis and chromatographic studies (TLC) were performed for proper identification and quality control these parameter include Results: Ash values, Total ash, (4.36%) acid insoluble ash, (3.23%) water soluble ash, (1.06%) Successive Extractive values in different solvent; petroleum ether (48.76%), diethyl ether (3.93%), chloroform (1.10%), ethyl acetate, (2.83%), acetone (0.70%), alcohol (1.80%), aqueous (4.96%), solubility in alcohol (32.0%) and water (8.26%), loss on drying (3.13%), pH at 1% (6.52), & 10% (5.91), bulk density (0.60%) and moisture content (5.0%). Conclusion: Preliminary phytochemical analysis of Sesamum seed showed presence of Alkaloid, steroids phenol and terpenoids carbohydrate and protein, which may be active compound, responsible for its wide activities.

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