ANTIOXIDANT, ANTIMICROBIAL ACTIVITY WITH MINERAL COMPOSITION AND LCMS BASED PHYTOCHEMICAL EVALUATION OF SOME MUCUNA SPECIES FROM INDIA

Author(s): S. S. Suryawanshi, M. R. Rane, P. R. Kshirsagar, P. P. Kamble, J. P. Jadhav

Abstract: The study was designed to demonstrate the phytochemical composition and to evaluate minerals, antioxidant and antibacterial activities of different Mucuna species. Liquid Column Mass Spectrometry (LC-MS) analysis was performed to identifies the phytoconstituents like phenolic, flavonoids, alkaloids, vitamins, amino acids, anti-cancer agent, antiretroviral agents, antidiabetic agents, anti-inflammatory and anti-Parkinson’s drug. Minerals essential for healthy functioning of the human body were resoluted from these species using atomic absorption spectroscopy. The antioxidant activity was evaluated by using the DPPH and ABTS assay. The antimicrobial activities of various Mucuna extracts were performed against some micro-organisms (Gram positive and Gram-negative micro-organism) using agar well diffusion method. The results of the present study revealed variation between some different Mucuna species. The results of LCMS phytochemical profiling indicate flavonoids and related polyphenols responsible for various pharmacological activities were the major compounds in the Mucuna seeds. Estimated mineral content in various Mucuna species shows the importance of these new wild varieties (Mucuna bracteata and Mucuna imbricata). Thus, serve as a great platform for the food industry due to their macro and micronutrients contents in significant amount. The strong antioxidant and antimicrobial activity present in the wild Mucuna imbricata seeds may be good alternative to the communally used of Mucuna species. They can also be used as a potential source of food and anti-Parkinson’s drug in the pharmaceutical industry. Thus, the present article puts focus on the possible use of two wild Mucuna species as a substitute for Mucuna pruriens var utilis and herbal remedy against neurodegenerative disorders.

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