SYNTHESIS OF 2,4,6-TRISUBSTITUTED PYRIMIDINE ANALOGUES VIA CHALCONE DERIVATIVES AND THEIR ANTICANCER EVALUATION

Author(s): Puspita Roy, Tanmoy Guria, Birendra Nath Karan, Subbiah Ramasamy, Tapan Kumar Maity*

Abstract: ABSTRACT A number of 2,4,6-trisubstituted pyrimidine derivatives 5a-f were synthesized from different chalcone moieties 3a-f. Compounds 3a–f were prepared from reaction between various substituted acetophenones 1a–c and various aromatic aldehydes 2a-d

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