Role of Oxidative Stress and Diabetes (Review Article)

Author(s): V. Asha Jyothi*, Giridhar Vedantam and Shahnaz Taskeen

Abstract: Diabetes mellitus is common problem of modern life style. It brings a complex series of pathological changes in patients with diabetes, most of them so complex that they are life threatening. The main cause for the pathological changes is the free radical increase due to oxidative stress. The need of the hour is to understand the mechanisms of free radical increase leading to oxidative stress which further progresses to the occurrence of pathological changes. The present review mainly focuses on the role free radicals in oxidative stress and role of oxidative stress on the pathological changes associated with oxidative stress increase in the diabetic condition.

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