Formulation and Evaluation of Chitosan Nanoparticles for Sustained Release of Clotrimazole (Research Article)

Author(s): Krishma Kumari, Archana Kaushik, Jasmine Kaur Bhatia, Diksha Gupta

Abstract: The main goal of the study was to develop and assess Chitosan nanoparticles for use in nanoparticle drug delivery systems to increase the therapeutic efficacy drug. Chitosan is employed as the polymer in this approach to create nanoparticles by using ionic gelation. Scanner electron microscopy (SEM), X-ray diffraction (XRD), entrapment efficiency, in vitro drug release investigations, and infrared (FTIR) spectral analysis are used to assess the prepared nanoparticles for external morphological analyses. Since there was no contact between the medication and the polymers, according to the Fourier transform IR spectra, they are compatible.

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