IMMUNOMODULATOR ACTIVITY OF SELAGINELLA BRYOPTERIS (L.) BAKER

Author(s): G. K. Mallaiah* and G. Krishna Mohan

Abstract: Selaginella bryopteris (L.) (family: Selaginaceae), commonly known as Sanjeevni, is a magical herb that has the power to cure any malady. The immunomodulatory activity studies like various haematological and serological tests were used to determine phagocytic activity, humoral antibody response, and cell mediated immune response using the carbon clearance test, sheep erythrocyte agglutination method, and delayed type of hypersensitivity reaction in mixed Swiss albino mice and Wister rats. In this study, different doses (100, 200, and 400 mg/kg body weight/day) of the methanolic extract and its bioactive fractions possessed promising immunostimulant properties.

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