Description of Pharmaceutical Tablet Punching Machine (Review Article)

Author(s): Sushma Desai⃰, Chandrashekara Rao Baru, Jyothi Aenugu and Vidhya Beebireddy

Abstract: Tablet press tool since its invention 19 century improving the efficiency of the basic model by studying various parameters, overcoming their problems, and developing into a fully automated machine meeting the demands of high quality with low-cost medicines production in time to ever-growing population, complying with cGMP (current good manufacturing practices) cleanliness standards, multiple ailments. Every pharmacy institution plans to have either of the tablets punching machine for sure. Various manufacturers develop their tablet press with improvised number of punches, stations, compression points and its speed. Hence there is a need to study and understand the whereabouts of pharmaceutical tablet punching machine like its principal, working and types of tablets prepared on them by any or combination of three established methods i.e., compression granulation, wet granulation, and direct compression. The common tableting process defects caused and to overcome these problems by the tablet press tooling and performance to be evaluated parameters are studied to estimate the working efficiency of the machine at every stage with the help of ISTMs (instrumented single tablet punching machine), IRTMs (instrumented rotary tablet punching machine) investigated with the achieved data is interpreted for selection of suitable tablet press to work on.

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