A Review and Possible Treatment Mechanisms against Covid-19 (Review Article)

Author(s): M Sharan, N Vaishnav2 and A K Jha

Abstract: A human coronavirus, which has caused an outbreak of COVID-19, has caused pandemic which commenced in December (2019) from Wuhan (China). This SARS-CoV-2 virus has so far infected more than four million people and killing more than 310,000 up to May 17, 2020. Based on phylogenetic relationship and genomic structure, this virus belongs to genera Beta coronavirus. In a study, Leila M. (2020) observed that Human Beta coronaviruses like SARS, MERS and SARS-CoV-2 have similarities, but also differences in pathogenetic characters influenced by their genomic and phenotypic structure. Till now the disease in laboratories, is being diagnosed by the RT-PCR with RLAMP under the possible better testing kit consideration. As we know only antiviral treatments are can halt the epidemic, but no vaccines have been successfully discovered but in the given paper, the possibilities have been discussed by using the antisense treatment and M protein targeting and old and proposed diagnosis along with reviewing the whole COVID-19 pandemic and its epidemiology.

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