Antimicrobial Activity of Ginger (Zingiber officinale Roscoe) Found in Manipur

Author(s): Vijayalaxmi Yumnam, Thongam Nabakumar Singh*, KH Sulochana Devi and Kananbala Sarangthem

Abstract: Due to indiscriminate use of antibiotics, antibiotic resistance has become a very common phenomenon. As such there is a need to search for plant based bioactive compound that can be harvested and used sensitively against microbes. Ginger, the spice has rich constituents of metabolites and is widely known for its therapeutic properties. Gas chromatography mass spectrometry (GCMS) analysis of the methanolic (Me), ethanolic (Et), petroleum ether (Pt) and water (Wa) extract of ginger reveals the presence of Zingerone (10.19% - 25.98%), [6]-shogaol (9.13% - 22.35%); [6]-gingerol (3.52% - 9.48%) as the major components. Antimicrobial studies on the Me, Et, Pt, Wa ginger extract and zingerone were conducted using two bacteria each of gram positive (Staphylococcus aureus, Enterococcus faecalis), two gram negative (Salmonella typhi, Escherichia coli) and two clinical isolates (Bacillus subtilis, Shigella flexnari). The antimicrobial test was conducted by adopting agar well diffusion method and the results showed bactericidal activity to both gram positive and gram-negative bacteria (pure culture or clinical isolates) with greater efficiency on gram positive bacteria, thus indicate that ginger extract may have various pharmaceutical applications.

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