Study on the Effect of Alcoholism on Pharmacodynamic Interactions Among Diabetic Patients Treated with Insulin in Tertiary Care Hospital

Author(s): Mounika A and Sumalatha G*

Abstract: Aim: To study the effect of alcoholism on pharmacodynamic interactions among diabetic patients treated with Insulin in Osmania general hospital. Materials and Methods: A prospective observational study was conducted among the diabetic patients with and without alcoholism in general medicine (in-patient) department at Osmania general hospital over the period of six months. Data was collected from the collected prescriptions and entered in Microsoft Excel 2010 spreadsheet and analysis was done using multivariate analysis of variance (SPSS for Windows version 16.0 software). Results: The multivariate analysis of variance showed no significant association of diabetes with all the factors. It also showed a significant association between the number of DDIs in Insulin treated diabetic patients with gender (p=0.018), alcoholism (p=0.042) and comorbidity (p=0.049) respectively. Conclusion: The present study concluded that there is significant effect of alcoholism on the pharmacodynamic interactions in Insulin treated diabetic patients.

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