Extracellular Synthesis of Metal Nanoparticles by Azospirillum brasilense: Promising Antimicrobial, Anti-inflammatory, Antiproliferative and Anti-Angiogenic Agents

Author(s): H. P. Spoorthy, N. Chandra Mohana, B. R. Nuthan and S. Satish

Abstract: Emergence of antibiotic resistance has been a major concern; the Nano biotechnology has envisioned to meet this prerequisite challenge. In this present work we have evaluated the efficacy of zinc, copper and nickel nanomaterials biosynthesized from Azospirillum brasilense. The nanoparticles synthesised extracellularly were characterised using spectroscopic techniques such as UV-visible, FT-IR SEM and XRD. The synthesized nanoparticle was evaluated for antimicrobial against microbial pathogens. Few nanoparticles showed significant antimicrobial and anti-inflammatory activities. All the nanoparticles exhibited good antiproliferative and anti-angiogenic activity.

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