BIOCHEMICAL STUDIES OF INSECTICIDE RESISTANCE IN AEDES AEGYPTI BY USING AN ORGANOPHOSPHATE (TEMEPHOS) INSECTICIDE

Author(s): S. Sridevi, T. Ramesh Kumar* and D. Nagarajan

Abstract: Mosquito borne diseases are dramatically affect public health and represent a major burden in terms of economy and development worldwide. Vector borne diseases are global problem it is trend that may only increases if global temperature rises and demographic trends continue and their economic and social impact are enormous. The mosquitoes control largely relies on insecticide applied to control the larval habitats, indoors against adult mosquito population worldwide and there is evidence that it has compromised the success of control interventions. Insecticide play a vital role in the fight against the diseases by controlling the vectors in order to improve the public health and however resistance to commonly used insecticides such as temephos. The present study was carried out to determine the metabolic resistance of detoxifying enzyme level in the resistant strain of five generation of Aedes aegypti. Biochemical analysis was done on Aedes (stegomyia) aegypti mosquitoes to determine the activities of enzymes such as α and β esterases, MFO, GST and AchE. These tests were performed in five generation of resistant strain of Aedes aegypti. The resistant generation shows the increased mean value compared with the control and susceptible strain. This result indicates the detoxifying enzyme level was progressively increased from R1 to R2 and shows a level of significant was 0.001. The result of present observation was indicating the resistance would develop among the population of Aedes aegypti.

PAGES: 184-188  |  52 VIEWS  175 DOWNLOADS