SYNTHESIS AND EVALUATION OF ASPIRIN ASSISTED BY MICROWAVE OVEN

Author(s): *Ajay Dongarwar, Vivek Wanjari, Chetan Maske, Tulsidas Nimbekar

Abstract: Microwave synthetic methods were devised for three lab reactions. The synthesis of Aspirin. These reactions are all done in either general chemistry or organic chemistry. Under conventional heating methods, the aspirin synthesis requires heating at 55 °C for 30 minutes. The proposed microwave methods provide shorter reaction times (7 min. at 175 watts) while maintaining similar, if not better, yields. The aspirin and phenytoin syntheses were shortened to 7 minutes, and the Claisen condensation was shortened to 4.5 minutes. The microwave method produced a 85.88% yield for aspirin, while conventional yield was 72.08%.

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