IN VITRO ANTIMICROBIAL ACTIVITY OF DIFFERENT SOLVENT EXTRACTS OF ANNONA MURICATA

Author(s): S.V.P Easwari, B Vasanthakumari and Rajesh Ramachandran

Abstract: Annona muricata is a member of the Annonaceae family and is a fruit tree with a long history of traditional use. A wide array of ethnomedicinal activities is contributed to different parts of A. muricata, and indigenous communities in Africa and South America extensively use this plant in their folk medicine. Numerous investigations have substantiated these activities, including anticancer, anticonvulsant, anti-arthritic, antiparasitic, antimalarial, hepatoprotective and antidiabetic activities. This research aimed to evaluate the potential antimicrobial effects from extracts of leaves of soursop by agar well diffusion method. The100 μl of methanolic extract inhibited Streptococcus mutans(20mm), Klebsiella pneumonia (22mm), Staphylococcus aureus (20mm), Pseudomonas aeroginosa (21mm). and Escherichia coli (22mm). The100 μl of ethanolic extract inhibited Enterococcus (20mm), Klebsiella pneumonia (18mm), Staphylococcus aureus (20mm), and Escherichia coli (20mm). In klebsiella pneumonia, E. coli and S. Aureus methanolic extracts were found to be having more inhibitory activity than ethanolic extracts. In Candida albicans the100 μl methanolic extract of Annona muricata obtained an inhibition zone of 20mm and in Aspergillus niger it showed an inhibition zone of 15mm. The antimicrobial activity of the tested extracts are comparable with the standard drugs.

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