ULTRASOUND ASSISTED SYNTHESIS OF CHLORO-SUBSTITUTED CHALCONES FOR THEIR ANTIFUNGAL ACTIVITY

Author(s): N. J. Deshmukh, G. D. Kottapalle and A. T. Shinde*

Abstract: Claisen- Schmidt condensation of chloro-substituted 2-acetyl-1-naphthol with aromatic aldehydes catalyzed by alkali results chalcones in 80-85% yield in alcoholic solvent under ultrasonic condition. The synthesized compounds are evaluated for their antifungal activity, the result showed all the compounds (3a-3f) showed good to moderate antifungal activity.

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